Assay Detail
Functional
CHEMBL863438
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Antiproliferative activity on human PBMC
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PBMC |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Biphenyl-4-ylcarbamoyl thiophene carboxylic acids as potent DHODH inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.23 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL199347 | — | — | 1 | 5.70 |
| CHEMBL199361 | — | — | 1 | 5.70 |
| CHEMBL200895 | — | — | 1 | 4.82 |
| CHEMBL371732 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL199347 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL199361 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL200895 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL371732 | — | IC50 | = | 20000.0 | nM | 4.70 |