Assay Detail
Binding
CHEMBL863882
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against src
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.91 | 5.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL197603 | — | — | 1 | 5.04 |
| CHEMBL370773 | — | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL197603 | — | IC50 | = | 9050.0 | nM | 5.04 |
| CHEMBL370773 | — | IC50 | = | 17150.0 | nM | 4.77 |