Assay Detail
Binding
CHEMBL863919
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Inhibitory activity against MMP2
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: mode of binding in a complex with MMP-8.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.24 | 4.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200435 | — | — | 1 | 4.24 |
| CHEMBL200385 | — | — | 1 | - |
| CHEMBL197921 | — | — | 1 | - |
| CHEMBL41928 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200435 | — | IC50 | = | 58000.0 | nM | 4.24 |
| CHEMBL200385 | — | IC50 | = | 685000.0 | nM | - |
| CHEMBL197921 | — | IC50 | > | 380000.0 | nM | - |
| CHEMBL41928 | — | IC50 | > | 120000.0 | nM | - |