Assay Detail
ADMET
CHEMBL864189
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Cytotoxicity against human SW620 cell line by clonogenic plating efficiency assay after 72 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | SW-620 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Semisynthetic maytansine analogues for the targeted treatment of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 10.40 | 10.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL378080 | — | — | 1 | 10.40 |
| CHEMBL292702 | MAYTANSINE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL378080 | — | IC50 | = | 0.04 | nM | 10.40 |
| CHEMBL292702 | MAYTANSINE | IC50 | > | 0.1 | nM | - |