Assay Detail
Binding
CHEMBL864485
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against VEGFR2 kinase
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Synthesis of a novel biotin-tagged photoaffinity probe for VEGF receptor tyrosine kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.53 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150315 | — | — | 1 | 5.82 |
| CHEMBL199725 | — | — | 1 | 5.82 |
| CHEMBL200085 | — | — | 1 | 5.32 |
| CHEMBL199460 | — | — | 1 | 5.15 |
| CHEMBL199573 | — | — | 1 | - |
| CHEMBL382716 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150315 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL199725 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL200085 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL199460 | — | IC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL199573 | — | IC50 | < | 1000.0 | nM | - |
| CHEMBL382716 | — | IC50 | < | 1000.0 | nM | - |