Assay Detail
Binding
CHEMBL864628
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MIF
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Macrophage migration inhibitory factor (CHEMBL2085) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Classification of chemical compounds by protein-compound docking for use in designing a focused library.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.32 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL199691 | — | — | 1 | 6.40 |
| CHEMBL201289 | — | — | 1 | 5.47 |
| CHEMBL201091 | — | — | 1 | 5.10 |
| CHEMBL201593 | — | — | 1 | 5.09 |
| CHEMBL199750 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL199691 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL201289 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL201091 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL201593 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL199750 | — | IC50 | = | 30000.0 | nM | 4.52 |