Assay Detail
Binding
CHEMBL864704
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to delta opioid receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.88 | 10.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL458631 | — | — | 1 | 10.51 |
| CHEMBL2375157 | — | — | 1 | 10.46 |
| CHEMBL501451 | — | — | 1 | 10.38 |
| CHEMBL208683 | — | — | 1 | 7.96 |
| CHEMBL377392 | — | — | 1 | 7.57 |
| CHEMBL211543 | — | — | 1 | 6.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL458631 | — | Ki | = | 0.031 | nM | 10.51 |
| CHEMBL2375157 | — | Ki | = | 0.035 | nM | 10.46 |
| CHEMBL501451 | — | Ki | = | 0.042 | nM | 10.38 |
| CHEMBL208683 | — | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL377392 | — | Ki | = | 27.2 | nM | 7.57 |
| CHEMBL211543 | — | Ki | = | 427.0 | nM | 6.37 |