Assay Detail
Binding
CHEMBL865523
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human NK1 receptor
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Discovery of 3,5-bis(trifluoromethyl)benzyl L-arylglycinamide based potent CCR2 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.19 | 6.19 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL378784 | — | — | 1 | 6.19 |
| CHEMBL211775 | — | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL378784 | — | IC50 | = | 650.0 | nM | 6.19 |
| CHEMBL211775 | — | Activity | = | 31.0 | % | - |
| CHEMBL211775 | — | IC50 | > | 100.0 | nM | - |