Assay Detail
Binding
CHEMBL865592
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Aminoalkyl phenyl sulfones--a novel series of 5-HT7 receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.17 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL204269 | — | — | 1 | 6.66 |
| CHEMBL203400 | — | — | 1 | 6.15 |
| CHEMBL202780 | — | — | 1 | 6.05 |
| CHEMBL379238 | — | — | 1 | 5.82 |
| CHEMBL204174 | — | — | 1 | - |
| CHEMBL380511 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL204269 | — | Ki | = | 220.0 | nM | 6.66 |
| CHEMBL203400 | — | Ki | = | 710.0 | nM | 6.15 |
| CHEMBL202780 | — | Ki | = | 900.0 | nM | 6.05 |
| CHEMBL379238 | — | Ki | = | 1500.0 | nM | 5.82 |
| CHEMBL204174 | — | Ki | - | — | - | |
| CHEMBL380511 | — | Ki | > | 1000.0 | nM | - |