Assay Detail
Binding
CHEMBL865877
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Inhibitory activity against YOP protein tyrosine phosphatase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Tyrosine-protein phosphatase YopH (CHEMBL4404) ↗| Type | SINGLE PROTEIN |
| Organism | Yersinia enterocolitica |
Publication
PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.81 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200117 | — | — | 1 | 6.26 |
| CHEMBL202197 | — | — | 1 | 5.92 |
| CHEMBL201662 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200117 | — | IC50 | = | 550.0 | nM | 6.26 |
| CHEMBL202197 | — | IC50 | = | 1190.0 | nM | 5.92 |
| CHEMBL201662 | — | IC50 | = | 5710.0 | nM | 5.24 |