Assay Detail
Functional
CHEMBL865990
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of anti CD3-induced IL2 secretion in mouse EL4 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | EL4 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.16 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL209148 | — | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL209148 | — | IC50 | = | 70.0 | nM | 7.16 |