Assay Detail
Binding
CHEMBL866129
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Binding affinity to human adrenergic Alpha-1D receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Design and synthesis of selective alpha1B adrenoceptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.42 | 7.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL541129 | — | — | 1 | 7.66 |
| CHEMBL537651 | — | — | 1 | 7.43 |
| CHEMBL537428 | — | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL541129 | — | Ki | = | 22.0 | nM | 7.66 |
| CHEMBL537651 | — | Ki | = | 37.0 | nM | 7.43 |
| CHEMBL537428 | — | Ki | = | 69.0 | nM | 7.16 |