Assay Detail
Binding
CHEMBL866298
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Binding affinity to human bradykinin B2 receptor transfected in CHO cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Bradykinin antagonists modified with dipeptide mimetic beta-turn inducers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.70 | 10.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2028850 | ICATIBANT | 4.0 | 1 | 10.60 |
| CHEMBL267822 | — | — | 1 | 7.00 |
| CHEMBL218749 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2028850 | ICATIBANT | Ki | = | 0.02512 | nM | 10.60 |
| CHEMBL267822 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL218749 | — | Ki | = | 3162.28 | nM | 5.50 |