Assay Detail
Functional
CHEMBL867902
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Survival of mouse F1 cells after 48 hrs by MTS reduction assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.48 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL379713 | — | — | 1 | 5.85 |
| CHEMBL378198 | — | — | 1 | 5.77 |
| CHEMBL379858 | — | — | 1 | 5.77 |
| CHEMBL377981 | — | — | 1 | 5.54 |
| CHEMBL211430 | — | — | 1 | 5.51 |
| CHEMBL213077 | — | — | 1 | 5.27 |
| CHEMBL212581 | — | — | 1 | 5.26 |
| CHEMBL210104 | — | — | 1 | 5.25 |
| CHEMBL373834 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL379713 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL378198 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL379858 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL377981 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL211430 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL213077 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL212581 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL210104 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL373834 | — | IC50 | = | 8000.0 | nM | 5.10 |