Assay Detail
Functional
CHEMBL868068
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Cytotoxicity against human H9 lymphocytes
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.57 | 4.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL215572 | — | — | 1 | 4.62 |
| CHEMBL211684 | — | — | 1 | 4.54 |
| CHEMBL266607 | — | — | 1 | 4.54 |
| CHEMBL211369 | — | — | 1 | - |
| CHEMBL211376 | — | — | 1 | - |
| CHEMBL215571 | — | — | 1 | - |
| CHEMBL214175 | — | — | 1 | - |
| CHEMBL380308 | — | — | 1 | - |
| CHEMBL404519 | BEVIRIMAT | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL215572 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL211684 | — | IC50 | = | 28500.0 | nM | 4.54 |
| CHEMBL266607 | — | IC50 | = | 28500.0 | nM | 4.54 |
| CHEMBL211369 | — | IC50 | > | 42700.0 | nM | - |
| CHEMBL211376 | — | IC50 | > | 45100.0 | nM | - |
| CHEMBL215571 | — | IC50 | > | 42700.0 | nM | - |
| CHEMBL214175 | — | IC50 | > | 42700.0 | nM | - |
| CHEMBL380308 | — | IC50 | > | 32600.0 | nM | - |
| CHEMBL404519 | BEVIRIMAT | IC50 | > | 42800.0 | nM | - |