Assay Detail
Functional
CHEMBL868080
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of membrane fusion between HIV1 NL4-3 envelope gene expressing COS cells and TZM cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | TZM |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.01 | 8.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137752 | — | — | 1 | 8.07 |
| CHEMBL214175 | — | — | 1 | 5.45 |
| CHEMBL215572 | — | — | 1 | 5.28 |
| CHEMBL215571 | — | — | 1 | 5.23 |
| CHEMBL404519 | BEVIRIMAT | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137752 | — | EC50 | = | 8.6 | nM | 8.07 |
| CHEMBL214175 | — | EC50 | = | 3580.0 | nM | 5.45 |
| CHEMBL215572 | — | EC50 | = | 5210.0 | nM | 5.28 |
| CHEMBL215571 | — | EC50 | = | 5850.0 | nM | 5.23 |
| CHEMBL404519 | BEVIRIMAT | EC50 | > | 17100.0 | nM | - |