Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL868411

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human liver alpha-L-fucosidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Tissue alpha-L-fucosidase (CHEMBL4176)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols.
Greimel P, Häusler H, Lundt I, Rupitz K, Stütz AE, Tarling CA, Withers SG, Wrodnigg TM.
Bioorg Med Chem Lett (2006) 16 : 2067 -2070
PubMed 16481162 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.15 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL314772 DEOXYFUCONOJIRIMYCIN 1 8.00
CHEMBL205277 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL314772 DEOXYFUCONOJIRIMYCIN Ki = 10.0 nM 8.00
CHEMBL205277 Ki = 500.0 nM 6.30