Assay Detail
Binding
CHEMBL868614
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CamK2alpha
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CHEMBL4147) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.10 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL213618 | — | — | 1 | 5.10 |
| CHEMBL388978 | STAUROSPORINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL213618 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL388978 | STAUROSPORINE | IC50 | > | 1.0 | nM | - |