Assay Detail
Binding
CHEMBL868756
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Inhibitory activity against Bacillus licheniformis alpha amylase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus licheniformis |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Sulfonamide chalcone as a new class of alpha-glucosidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.42 | 4.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL199442 | — | — | 1 | 4.78 |
| CHEMBL382280 | — | — | 1 | 4.43 |
| CHEMBL371723 | — | — | 1 | 4.06 |
| CHEMBL200185 | — | — | 1 | - |
| CHEMBL200194 | — | — | 1 | - |
| CHEMBL383563 | — | — | 1 | - |
| CHEMBL200485 | — | — | 1 | - |
| CHEMBL199829 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL199442 | — | IC50 | = | 16800.0 | nM | 4.78 |
| CHEMBL382280 | — | IC50 | = | 37300.0 | nM | 4.43 |
| CHEMBL371723 | — | IC50 | = | 87800.0 | nM | 4.06 |
| CHEMBL200185 | — | IC50 | - | — | - | |
| CHEMBL200194 | — | IC50 | - | — | - | |
| CHEMBL383563 | — | IC50 | = | 268900.0 | nM | - |
| CHEMBL200485 | — | IC50 | - | — | - | |
| CHEMBL199829 | — | IC50 | = | 193700.0 | nM | - |