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Assay Detail

CHEMBL869121

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Binding
Binding affinity to plasmin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Plasminogen (CHEMBL1801)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Novel, potent, selective, and orally bioavailable human betaII-tryptase inhibitors.
Sperandio D, Tai VW, Lohman J, Hirschbein B, Mendonca R, Lee CS, Spencer JR, Janc J, Nguyen M, Beltman J, Sprengeler P, Scheerens H, Lin T, Liu L, Gadre A, Kellogg A, Green MJ, McGrath ME.
Bioorg Med Chem Lett (2006) 16 : 4085 -4089
PubMed 16725321 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.37 6.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL211561 1 6.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL211561 Ki = 430.0 nM 6.37