Assay Detail
Binding
CHEMBL869162
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Binding affinity to human kFABP
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.02 | 8.52 |
| Kd | 1 | 6.10 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL212860 | — | — | 1 | 8.52 |
| CHEMBL437489 | — | — | 1 | 8.05 |
| CHEMBL378857 | — | — | 1 | 7.48 |
| CHEMBL82293 | PALMITIC ACID | -1.0 | 1 | 6.10 |
| CHEMBL378181 | — | — | 1 | - |
| CHEMBL210078 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL212860 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL437489 | — | Ki | = | 9.0 | nM | 8.05 |
| CHEMBL378857 | — | Ki | = | 33.0 | nM | 7.48 |
| CHEMBL82293 | PALMITIC ACID | Kd | = | 802.0 | nM | 6.10 |
| CHEMBL378181 | — | Ki | < | 2.0 | nM | - |
| CHEMBL210078 | — | Ki | > | 2000.0 | nM | - |