Assay Detail
Binding
CHEMBL869172
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Saccharomyces cerevisiae ODCase at 25 degreeC by competitive binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Orotidine 5'-phosphate decarboxylase (CHEMBL4858) ↗| Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
Publication
Design of inhibitors of orotidine monophosphate decarboxylase using bioisosteric replacement and determination of inhibition kinetics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 7.19 | 7.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463480 | 6-AZA-URIDINE MONOPHOSPHATE | — | 1 | 7.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463480 | 6-AZA-URIDINE MONOPHOSPHATE | Ki | = | 64.0 | nM | 7.19 |