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Assay Detail

CHEMBL869588

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of diltiazem sensitive L type calcium channel by radioligand cellular uptake inhibition assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Voltage-gated L-type calcium channel (CHEMBL2095229)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

(R)-sila-venlafaxine: a selective noradrenaline reuptake inhibitor for the treatment of emesis.
Showell GA, Barnes MJ, Daiss JO, Mills JS, Montana JG, Tacke R, Warneck JB.
Bioorg Med Chem Lett (2006) 16 : 2555 -2558
PubMed 16513343 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.57 5.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL427215 1 5.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL427215 IC50 = 2700.0 nM 5.57