Assay Detail
Binding
CHEMBL869843
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CA2
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
N-hydroxyurea--a versatile zinc binding function in the design of metalloenzyme inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.53 | 6.51 |
| IC50 | 1 | 4.33 | 4.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL213348 | — | — | 1 | 6.51 |
| CHEMBL467 | HYDROXYUREA | 4.0 | 1 | 4.55 |
| CHEMBL734 | ACETOHYDROXAMIC ACID | 4.0 | 1 | 4.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL213348 | — | Ki | = | 310.0 | nM | 6.51 |
| CHEMBL467 | HYDROXYUREA | Ki | = | 28000.0 | nM | 4.55 |
| CHEMBL734 | ACETOHYDROXAMIC ACID | IC50 | = | 47000.0 | nM | 4.33 |