Assay Detail
Functional
CHEMBL869947
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Inhibition of TXB2 production in human whole blood
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibition of cytosolic phospholipase A2alpha: hit to lead optimization.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.13 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL383420 | — | — | 1 | 5.85 |
| CHEMBL372790 | — | — | 1 | 5.08 |
| CHEMBL371226 | — | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL383420 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL372790 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL371226 | — | IC50 | = | 34000.0 | nM | 4.47 |