Assay Detail
Functional
CHEMBL869948
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Inhibition of LTB4 production in human whole blood
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibition of cytosolic phospholipase A2alpha: hit to lead optimization.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.26 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL383420 | — | — | 1 | 6.05 |
| CHEMBL372790 | — | — | 1 | 5.20 |
| CHEMBL371226 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL383420 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL372790 | — | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL371226 | — | IC50 | = | 30000.0 | nM | 4.52 |