Assay Detail
Binding
CHEMBL870416
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 14 | 7.63 | 9.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL210005 | — | — | 1 | 9.62 |
| CHEMBL377789 | — | — | 1 | 9.13 |
| CHEMBL214104 | — | — | 1 | 8.41 |
| CHEMBL58646 | — | — | 1 | 8.28 |
| CHEMBL378355 | — | — | 1 | 8.00 |
| CHEMBL215594 | — | — | 1 | 7.92 |
| CHEMBL60869 | — | — | 1 | 7.64 |
| CHEMBL213291 | — | — | 1 | 7.33 |
| CHEMBL209550 | — | — | 1 | 7.23 |
| CHEMBL212434 | — | — | 1 | 7.14 |
| CHEMBL215760 | — | — | 1 | 6.96 |
| CHEMBL1162933 | — | — | 1 | 6.77 |
| CHEMBL213880 | — | — | 1 | 6.68 |
| CHEMBL293103 | — | — | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL210005 | — | Ki | = | 0.24 | nM | 9.62 |
| CHEMBL377789 | — | Ki | = | 0.74 | nM | 9.13 |
| CHEMBL214104 | — | Ki | = | 3.9 | nM | 8.41 |
| CHEMBL58646 | — | Ki | = | 5.2 | nM | 8.28 |
| CHEMBL378355 | — | Ki | = | 9.9 | nM | 8.00 |
| CHEMBL215594 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL60869 | — | Ki | = | 23.0 | nM | 7.64 |
| CHEMBL213291 | — | Ki | = | 47.0 | nM | 7.33 |
| CHEMBL209550 | — | Ki | = | 59.0 | nM | 7.23 |
| CHEMBL212434 | — | Ki | = | 72.0 | nM | 7.14 |
| CHEMBL215760 | — | Ki | = | 110.0 | nM | 6.96 |
| CHEMBL1162933 | — | Ki | = | 170.0 | nM | 6.77 |
| CHEMBL213880 | — | Ki | = | 210.0 | nM | 6.68 |
| CHEMBL293103 | — | Ki | = | 2100.0 | nM | 5.68 |