Assay Detail
Functional
CHEMBL870712
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Inhibition of Plasmodium falciparum 3D7
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.30 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL205338 | FR-900098 | — | 1 | 6.62 |
| CHEMBL204406 | — | — | 1 | 6.50 |
| CHEMBL203125 | FOSMIDOMYCIN | 3.0 | 1 | 6.40 |
| CHEMBL205091 | — | — | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL205338 | FR-900098 | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL204406 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL203125 | FOSMIDOMYCIN | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL205091 | — | IC50 | = | 2100.0 | nM | 5.68 |