Assay Detail
Functional
CHEMBL871133
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonistic efficacy at human delta opioid receptor by [35S]GTP-gammaS binding assay
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and biological activity of the first cyclic biphalin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.08 | 9.06 |
| Emax | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200129 | — | — | 2 | 9.06 |
| CHEMBL200199 | BIPHALIN | — | 2 | 8.60 |
| CHEMBL372787 | — | — | 2 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200129 | — | IC50 | = | 0.87 | nM | 9.06 |
| CHEMBL200199 | BIPHALIN | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL372787 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL200199 | BIPHALIN | Emax | = | 27.0 | % | - |
| CHEMBL372787 | — | Emax | = | 58.0 | % | - |
| CHEMBL200129 | — | Emax | = | 100.0 | % | - |