Assay Detail
Binding
CHEMBL871672
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Binding affinity towards human DP receptor expressed in CHO cells
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 5.28 | 5.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL373294 | — | — | 1 | 5.73 |
| CHEMBL197398 | — | — | 1 | 5.31 |
| CHEMBL196617 | — | — | 1 | 5.16 |
| CHEMBL364299 | — | — | 1 | 5.11 |
| CHEMBL199040 | — | — | 1 | 5.07 |
| CHEMBL370257 | — | — | 1 | - |
| CHEMBL196707 | — | — | 1 | - |
| CHEMBL193753 | — | — | 1 | - |
| CHEMBL194019 | — | — | 1 | - |
| CHEMBL194918 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL373294 | — | Ki | = | 1872.0 | nM | 5.73 |
| CHEMBL197398 | — | Ki | = | 4860.0 | nM | 5.31 |
| CHEMBL196617 | — | Ki | = | 6890.0 | nM | 5.16 |
| CHEMBL364299 | — | Ki | = | 7710.0 | nM | 5.11 |
| CHEMBL199040 | — | Ki | = | 8460.0 | nM | 5.07 |
| CHEMBL370257 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL196707 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL193753 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL194019 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL194918 | — | Ki | > | 10000.0 | nM | - |