Assay Detail
Functional
CHEMBL872005
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In vitro inhibitory concentration of compound against human cancer RXF 944 cell line was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RXF 944 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and in vitro efficacy of acid-sensitive poly(ethylene glycol) paclitaxel conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.18 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 7.30 |
| CHEMBL384552 | — | — | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL384552 | — | IC50 | = | 90.0 | nM | 7.05 |