Assay Detail
Binding
CHEMBL872218
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Inhibitory concentration against dopamine receptor D4
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Designed multiple ligands. An emerging drug discovery paradigm.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.22 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL69584 | — | — | 1 | 8.80 |
| CHEMBL320597 | — | — | 1 | 8.70 |
| CHEMBL107742 | — | — | 1 | 8.52 |
| CHEMBL42 | CLOZAPINE | 4.0 | 1 | 6.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL69584 | — | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL320597 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL107742 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL42 | CLOZAPINE | IC50 | = | 138.0 | nM | 6.86 |