Assay Detail
Binding
CHEMBL872289
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Binding affinity towards mouse spleen cannabinoid receptor 2 in the presence of PMSF upon incubation for 15 min at 4 degree C in pH 7.4 using [3H]CP-55940
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Tissue | Spleen |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
High affinity electrophilic and photoactivatable covalent endocannabinoid probes for the CB1 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.12 | 7.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2113101 | — | — | 1 | 7.31 |
| CHEMBL2113102 | — | — | 1 | 7.24 |
| CHEMBL418353 | — | — | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2113101 | — | Ki | = | 48.5 | nM | 7.31 |
| CHEMBL2113102 | — | Ki | = | 57.6 | nM | 7.24 |
| CHEMBL418353 | — | Ki | = | 157.0 | nM | 6.80 |