Assay Detail
Binding
CHEMBL872339
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Binding affinity towards 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis, biological activity and quantitative structure-activity relationships of N-substituted-3,4-dihydro-2H-1-benzopyran derivatives
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.63 | 7.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL416523 | — | — | 1 | 7.31 |
| CHEMBL11425 | — | — | 1 | 7.25 |
| CHEMBL11592 | — | — | 1 | 6.00 |
| CHEMBL417608 | — | — | 1 | 5.11 |
| CHEMBL438755 | — | — | 1 | 5.00 |
| CHEMBL11409 | — | — | 1 | 4.95 |
| CHEMBL11262 | — | — | 1 | 4.80 |
| CHEMBL275481 | — | — | 1 | 4.61 |
| CHEMBL416336 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL416523 | — | IC50 | = | 48.98 | nM | 7.31 |
| CHEMBL11425 | — | IC50 | = | 56.23 | nM | 7.25 |
| CHEMBL11592 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL417608 | — | IC50 | = | 7762.47 | nM | 5.11 |
| CHEMBL438755 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL11409 | — | IC50 | = | 11220.18 | nM | 4.95 |
| CHEMBL11262 | — | IC50 | = | 15848.93 | nM | 4.80 |
| CHEMBL275481 | — | IC50 | = | 24547.09 | nM | 4.61 |
| CHEMBL416336 | — | IC50 | = | 213796.21 | nM | - |