Assay Detail
Binding
CHEMBL872484
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Binding affinity against cytidine deaminase of human liver
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Cyclic urea nucleosides. Cytidine deaminase activity as a function of aglycon ring size.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.35 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL610997 | — | — | 1 | 7.60 |
| CHEMBL2311129 | — | — | 1 | 7.40 |
| CHEMBL2367576 | — | — | 1 | 6.40 |
| CHEMBL608656 | — | — | 1 | 5.55 |
| CHEMBL609349 | — | — | 1 | 4.82 |
| CHEMBL608655 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL610997 | — | Ki | = | 25.0 | nM | 7.60 |
| CHEMBL2311129 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL2367576 | — | Ki | = | 400.0 | nM | 6.40 |
| CHEMBL608656 | — | Ki | = | 2800.0 | nM | 5.55 |
| CHEMBL609349 | — | Ki | = | 15000.0 | nM | 4.82 |
| CHEMBL608655 | — | Ki | = | 300000.0 | nM | - |