Assay Detail
Binding
CHEMBL872560
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Inhibition of MMP-8
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Novel inhibitors of procollagen C-proteinase. Part 2: glutamic acid hydroxamates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.88 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80486 | — | — | 1 | 8.22 |
| CHEMBL432532 | — | — | 1 | 8.05 |
| CHEMBL449092 | — | — | 1 | 5.16 |
| CHEMBL311367 | — | — | 1 | 4.89 |
| CHEMBL262758 | — | — | 1 | 4.52 |
| CHEMBL307057 | — | — | 1 | 4.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80486 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL432532 | — | Ki | = | 9.0 | nM | 8.05 |
| CHEMBL449092 | — | Ki | = | 7000.0 | nM | 5.16 |
| CHEMBL311367 | — | Ki | = | 13000.0 | nM | 4.89 |
| CHEMBL262758 | — | Ki | = | 30000.0 | nM | 4.52 |
| CHEMBL307057 | — | Ki | = | 35000.0 | nM | 4.46 |