Assay Detail
Functional
CHEMBL872623
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In vitro antibacterial activity against Lactobacillus casei (ATCC 7469)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Lacticaseibacillus casei |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
10-Propargylaminopterin and alkyl homologues of methotrexate as inhibitors of folate metabolism.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.84 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34259 | METHOTREXATE | 4.0 | 1 | 7.89 |
| CHEMBL166915 | — | — | 1 | 7.85 |
| CHEMBL171757 | — | — | 1 | 7.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34259 | METHOTREXATE | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL166915 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL171757 | — | IC50 | = | 17.0 | nM | 7.77 |