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Assay Detail

CHEMBL872695

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for cytotoxicity against Mac15A cell lines.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type MAC15A
Confidence 1 — Organism
Curated By Intermediate

Target

MAC15A (CHEMBL614121)
Type CELL-LINE
Organism Mus musculus

Publication

Novel imidazothioxanthones: Synthesis, DNA binding and cytotoxicity
Varvaresou A, Tsotinis A, Siatra-Papastaikoudi T, Papadaki-Valiraki A, Thurston D, Jenkins T, Kelland L
Bioorg Med Chem Lett (1996) 6 : 865 -870
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.48 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL169245 1 6.75
CHEMBL171056 1 6.38
CHEMBL171004 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL169245 IC50 = 180.0 nM 6.75
CHEMBL171056 IC50 = 420.0 nM 6.38
CHEMBL171004 IC50 = 500.0 nM 6.30