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Assay Detail

CHEMBL872708

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for in vitro inhibitory activity against cynomolgus monkey Steroid 5-alpha-reductase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cercopithecidae
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibition of steroid 5-reductase by 3-nitrosteroids: synthesis, mechanism of inhibition, and in vivo activity.
Holt DA, Levy MA, Yen H, Oh H, Metcalf BW, Wier PJ
Bioorg Med Chem Lett (1991) 1 : 27 -32
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.40 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL278283 1 8.40
CHEMBL110001 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL278283 Ki = 4.0 nM 8.40
CHEMBL110001 Ki < 1.0 nM -