Assay Detail
Binding
CHEMBL872915
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding ability of compound at cloned human 5-hydroxytryptamine 2A receptor using [3H]ketanserin as radioligand
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Substituted naphthofurans as hallucinogenic phenethylamine-ergoline hybrid molecules with unexpected muscarinic antagonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.30 | 7.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL305275 | — | — | 1 | 7.97 |
| CHEMBL445106 | — | — | 1 | 6.62 |
| CHEMBL307770 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL305275 | — | Ki | = | 10.7 | nM | 7.97 |
| CHEMBL445106 | — | Ki | = | 240.0 | nM | 6.62 |
| CHEMBL307770 | — | Ki | - | nM | - |