Assay Detail
Binding
CHEMBL872958
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Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing Opioid receptor delta 1
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HEK293 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
High-affinity, non-peptide agonists for the ORL1 (orphanin FQ/nociceptin) receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.37 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL283432 | — | — | 1 | 6.62 |
| CHEMBL27460 | — | — | 1 | 6.32 |
| CHEMBL27716 | — | — | 1 | 6.28 |
| CHEMBL284414 | — | — | 1 | 6.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL283432 | — | Ki | = | 240.0 | nM | 6.62 |
| CHEMBL27460 | — | Ki | = | 480.0 | nM | 6.32 |
| CHEMBL27716 | — | Ki | = | 530.0 | nM | 6.28 |
| CHEMBL284414 | — | Ki | = | 540.0 | nM | 6.27 |