Assay Detail
Binding
CHEMBL873057
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Overall binding displacement in tissues containing only the Alpha-1A adrenergic receptor from rat submaxillary gland
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.13 | 10.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25554 | — | — | 1 | 10.10 |
| CHEMBL420060 | — | — | 1 | 9.15 |
| CHEMBL267930 | SPIPERONE | 2.0 | 1 | 8.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25554 | — | Ki | = | 0.08 | nM | 10.10 |
| CHEMBL420060 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL267930 | SPIPERONE | Ki | = | 7.2 | nM | 8.14 |