Assay Detail
Binding
CHEMBL873236
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Binding affinity towards human Vasopressin V2 receptor
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and characterization of fluorescent antagonists and agonists for human oxytocin and vasopressin V(1)(a) receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 5.75 | 6.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1790712 | — | — | 1 | 6.03 |
| CHEMBL395429 | OXYTOCIN | 4.0 | 1 | 5.46 |
| CHEMBL1790722 | — | — | 1 | - |
| CHEMBL1790713 | — | — | 1 | - |
| CHEMBL1790718 | — | — | 1 | - |
| CHEMBL1790719 | — | — | 1 | - |
| CHEMBL1790728 | — | — | 1 | - |
| CHEMBL1790721 | — | — | 1 | - |
| CHEMBL1790729 | — | — | 1 | - |
| CHEMBL1790711 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1790712 | — | Ki | = | 930.0 | nM | 6.03 |
| CHEMBL395429 | OXYTOCIN | Ki | = | 3500.0 | nM | 5.46 |
| CHEMBL1790722 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1790713 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1790718 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1790719 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL1790728 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1790721 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1790729 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1790711 | — | Ki | > | 10000.0 | nM | - |