Assay Detail
Binding
CHEMBL873568
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration required for binding to mutant loopless TAR using electrophoretic mobility shift assays done at 25 degree C with pH 7.5
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Expert |
Publication
Antiviral 6-amino-quinolones: molecular basis for potency and selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.70 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL188588 | — | — | 1 | 6.89 |
| CHEMBL125002 | — | — | 1 | 6.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL188588 | — | EC50 | = | 130.0 | nM | 6.89 |
| CHEMBL125002 | — | EC50 | = | 320.0 | nM | 6.50 |