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Assay Detail

CHEMBL873623

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro binding activity against opioid receptor delta using [3H]DPDPE) as radioligand
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Delta-type opioid receptor (CHEMBL236)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

New 1-(heterocyclylalkyl)-4-(propionanilido)-4-piperidinyl methyl ester and methylene methyl ether analgesics.
Bagley JR, Thomas SA, Rudo FG, Spencer HK, Doorley BM, Ossipov MH, Jerussi TP, Benvenga MJ, Spaulding T.
J Med Chem (1991) 34 : 827 -841
PubMed 1847432 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.93 6.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL169366 1 6.09
CHEMBL168723 1 5.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL169366 IC50 = 809.0 nM 6.09
CHEMBL168723 IC50 = 1701.0 nM 5.77