Assay Detail
Binding
CHEMBL874556
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Inhibitory concentration against tyramine oxidase of Arthrobacter spp.; Competitive inhibition
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.37 | 6.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2093956 | — | — | 1 | 6.41 |
| CHEMBL2094027 | — | — | 1 | 5.44 |
| CHEMBL541373 | — | — | 1 | 5.43 |
| CHEMBL2093955 | — | — | 1 | 5.09 |
| CHEMBL1255743 | TRANYLCYPROMINE HYDROCHLORIDE | — | 1 | 4.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2093956 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL2094027 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL541373 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL2093955 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL1255743 | TRANYLCYPROMINE HYDROCHLORIDE | IC50 | = | 35000.0 | nM | 4.46 |