Assay Detail
Binding
CHEMBL874563
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Inhibition of Platelet-derived growth factor receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.03 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL57366 | — | — | 1 | 5.96 |
| CHEMBL49120 | PD-0166285 | 1.0 | 1 | 4.10 |
| CHEMBL299763 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL57366 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL49120 | PD-0166285 | IC50 | = | 79000.0 | nM | 4.10 |
| CHEMBL299763 | — | IC50 | > | 50000.0 | nM | - |