Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL875565

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity of compound towards dopamine receptor D3 was determined
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The role of QSAR in dopamine interactions.
Hansch C, Verma RP, Kurup A, Mekapati SB.
Bioorg Med Chem Lett (2005) 15 : 2149 -2157
PubMed 15808487 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 10 7.69 9.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL369367 1 9.60
CHEMBL426763 1 8.70
CHEMBL366679 1 8.57
CHEMBL177455 1 8.37
CHEMBL367045 1 8.08
CHEMBL176169 1 7.74
CHEMBL362060 1 6.99
CHEMBL367180 1 6.95
CHEMBL367875 1 6.56
CHEMBL177328 1 5.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL369367 Ki = 0.2512 nM 9.60
CHEMBL426763 Ki = 1.995 nM 8.70
CHEMBL366679 Ki = 2.692 nM 8.57
CHEMBL177455 Ki = 4.266 nM 8.37
CHEMBL367045 Ki = 8.318 nM 8.08
CHEMBL176169 Ki = 18.2 nM 7.74
CHEMBL362060 Ki = 102.33 nM 6.99
CHEMBL367180 Ki = 112.2 nM 6.95
CHEMBL367875 Ki = 275.42 nM 6.56
CHEMBL177328 Ki = 4265.8 nM 5.37