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Assay Detail

CHEMBL875993

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Ex vivo inhibition of platelet aggregation induced by ADP (600 uM) in cynomolgus monkey platelet rich plasma
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cercopithecidae
Tissue Plasma
Confidence 1 — Organism
Curated By Intermediate

Target

Monkey (CHEMBL614874)
Type ORGANISM
Organism Cercopithecidae

Publication

Development of dual-acting benzofurans for thromboxane A2 receptor antagonist and prostacyclin receptor agonist: synthesis, structure-activity relationship, and evaluation of benzofuran derivatives.
Ohno M, Miyamoto M, Hoshi K, Takeda T, Yamada N, Ohtake A.
J Med Chem (2005) 48 : 5279 -5294
PubMed 16078846 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.85 6.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL364529 1 6.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL364529 IC50 = 140.0 nM 6.85