Assay Detail
Functional
CHEMBL876064
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration of compound against growth of human pancreatic carcinoma cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MIA PaCa-2 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of novel rhodacyanine dyes that exhibit antitumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.27 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL106653 | — | — | 1 | 7.40 |
| CHEMBL108793 | — | — | 1 | 7.30 |
| CHEMBL280643 | — | — | 1 | 7.22 |
| CHEMBL108063 | — | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL106653 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL108793 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL280643 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL108063 | — | IC50 | = | 70.0 | nM | 7.16 |